Regina Mills

Regina Mills is one of the main protagonists of the TV series, Once Upon a Time. She was originally an antagonistic character, before later reforming. She is the daughter of Cora and Henry, the half-sister of Zelena, the stepmother of Snow White, the step-grandmother of Emma Swan and Neal Nolan, the step great-grandmother and adoptive mother of Henry Mills, and the step great-great-grandmother and adoptive grandmother of Lucy. Regina's adoptive son, Henry, made her reform her ways and make the full transition from villain to hero. Regina is a main character in OUAT S8 and a main character in Once Upon A Descendant.

Once Upon A Desendant
When Carlos, Mal, Evie, Jay, Ben, Audrey and Lonnie showed up In Storybrooke, Regina takes a liking to Carlos and Evie in particular (especially since the ladder is the evil queens daughter from another world) and agrees to help them find their friend and Carlos's girlfriend Jane, daughter of The Fairy Godmother